Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. [5] Neurexins are a family of proteins that function in the vertebrate nervous system as cell adhesion molecules …

2025年3月30日 · NRXN1 (Neurexin 1) is a Protein Coding gene. Diseases associated with NRXN1 include Chromosome 2P16.3 Deletion Syndrome and Pitt-Hopkins-Like Syndrome 2. …

Mutations in the NRXN1 gene (OMIM#600565) have been frequently detected in various neurodevelopmental disorders, particularly in individuals affected by severe developmental …

We present a medical record review of subjects with deletions involving exonic sequences of NRXN1. We ascertained cases from 3,540 individuals referred clinically for comparative …

NRXN1 is mutated in autosomal-recessive Pitt-Hopkins-like mental retardation and determines the level of a common synaptic protein in Drosophila. The findings of studies to date provide …

2025年1月5日 · Title: Functional abnormality in the sensorimotor system attributed to NRXN1 variants in boys with attention deficit hyperactivity disorder. Homozygous exonic and intragenic …

2023年12月3日 · Neurexins are cell-surface receptors that bind neuroligins to form Ca (2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This …

Neurexins 是细胞表面受体，它结合 neuroligins 以在中枢神经系统的突触处形成 CA (2+) 依赖性 neurexin/neuroligin 复合物。 该复合体是有效神经传递所必需的，并参与突触接触的形成。 该 …

2023年6月24日 · De novo mutations and copy number deletions in NRXN1 (2p16.3) pose a significant risk for schizophrenia (SCZ). It is unclear how NRXN1 deletions impact cortical …

2025年1月7日 · 什么是nrxn1基因？ NRXN1基因，全名neurexin 1，位于人类染色体的2p16.3位置。 这个基因的主要功能是编码蛋白质，属于Neurexins家族，这个家族在神经系统的发育和功 …