NOD1 is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing molecules …

Here we discuss recent developments about the mechanisms by which NOD1 and NOD2 are activated by bacterial ligands, the regulation of their signaling pathways, and their role in host …

2025年3月30日 · NOD1 (Nucleotide Binding Oligomerization Domain Containing 1) is a Protein Coding gene. Diseases associated with NOD1 include Blau Syndrome and Hematologic …

2022年3月22日 · NOD1 and NOD2 are two seminal NLRs that have been shown to sense specific bacterial ligands and have diverse immunomodulatory effects that are important for both host …

2013年12月13日 · NOD1 (nucleotide oligomerization domain-containing protein 1) and NOD2 are members of the NOD-like receptor family of proteins, which function to detect peptidoglycan …

2005年12月9日 · The NOD (nucleotide-binding oligomerization domain) proteins NOD1 and NOD2 have important roles in innate immunity as sensors of microbial components derived …

In this review, we will focus on the role of NOD1 and NOD2 in the recognition and response to intracellular pathogens, including Gram-positive and Gram-negative bacteria, and on their …

In this review, we will describe how NOD1 and NOD2 sense microbes and cellular stress to regulate host responses that can affect disease pathogenesis and outcomes. Keywords: …

2019年7月30日 · NOD1 and NOD2 are related intracellular sensors of bacterial peptidoglycan and belong to the Nod-like receptor (NLR) family of innate immune proteins that play fundamental …

2006年12月22日 · Nod1 activation mediates distinct cellular responses including activation of MAP kinases, IL-8 release, apoptosis and suppression of several estrogen-dependent …