LIMK2 Gene - GeneCards | LIMK2 Protein | LIMK2 Antibody
2025年3月30日 · LIMK2 (LIM Domain Kinase 2) is a Protein Coding gene. Diseases associated with LIMK2 include Williams-Beuren Syndrome and Autism Spectrum Disorder. Among its …
LIMK2 - Wikipedia
LIM domain kinase 2 is an enzyme that in humans is encoded by the LIMK2 gene. [5][6][7] There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they …
LIM kinase 2 (LIMK2) may play an essential role in platelet function
2020年3月1日 · The members of the LIM kinase family of proteins (LIMK1 and 2) regulate actin dynamics by controlling the binding affinity of ADF/cofilin towards actin. LIMK2 has two major …
LIMK2: A Multifaceted kinase with pleiotropic roles in human …
2023年7月1日 · LIMK2, a serine-specific kinase, was discovered as an actin dynamics regulating kinase. Emerging studies have shown its pivotal role in numerous human malignancies and …
LIM 结构域激酶 2（LIMK2）基因 | MCE - MCE-生物活性分子大师
LIM 激酶 1 和 LIM 激酶 2 属于一个小亚家族，具有 2 个 N 末端 LIM 基序和一个 C 末端蛋白激酶结构域的独特组合。 由该基因编码的蛋白质被 Rho 的下游效应子 ROCK 磷酸化和激活，编码的 …
LIMK2 LIM domain kinase 2 [ (human)] - National Center for ...
LIMK2 is a key regulator that acts through different substrates to provide functional links between the actin cytoskeleton and spindle dynamics. LIMK2 positively regulates the level of Aurora A, …
项目文章 | 药学TOP期刊PR&ChIP-seq助力揭示激酶LIMK2促进梗 …
2024年10月23日 · 该研究表明，LIMK2通过增强磷酸化β-连环蛋白（Ser552）和Lrp6信号，促进心肌梗死后肌成纤维细胞增殖和不良心脏重塑。 这提示LIMK2可能是心肌梗死后损伤治疗的一个 …
p53-Mediated transactivation of LIMK2b links actin dynamics …
2010年3月1日 · Here, we report the identification of LIMK2, which encodes a kinase that regulates actin dynamics through phosphorylation of cofilin, as a p53 target upregulated by DNA …
LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the
2023年3月4日 · LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2) are serine/threonine and tyrosine kinases and the only two members of the LIM kinase family. They play a crucial role in the …
LIMK2: A Multifaceted Kinase with pleiotropic roles in human …
2024年7月1日 · LIMK2, a serine-specific kinase, was discovered as an actin dynamics regulating kinase. Emerging studies have shown its pivotal role in numerous human malignancies and …