The cytokine interleukin-1β (IL-1β) is a key mediator of the inflammatory response. Essential for the host-response and resistance to pathogens, it also exacerbates damage during chronic …

IL-1β is the most studied member of the IL-1 family due to its role in mediating autoinflammatory diseases. 4 Unquestionably, IL-1β evolved to assist host defense against infection 5 and this …

IL-1β is a pro-inflammatory cytokine that has been implicated in pain, inflammation and autoimmune conditions. This review will focus on studies that shed light on the critical role of …

2025年3月30日 · IL1B (Interleukin 1 Beta) is a Protein Coding gene. Diseases associated with IL1B include Gastric Cancer and Diffuse Gastric And Lobular Breast Cancer Syndrome. …

Interleukin-1 (IL-1) is a cytokine which governs inflammatory responses by binding IL-1 α and β agonist with its receptor IL-1R (Vigers et al., 1997). IL-1β is synthesized by inflamasome …

2025年3月26日 · Interleukin-1beta moderates the relationships between middle frontal-mACC/insular connectivity and depressive symptoms in bipolar II depression. Intense impact …

This pathway summarizes extracellular and intracellular signaling of IL-1α or IL-1β, including positive- and negative-feedback mechanisms that amplify or terminate the IL-1 response.

2019年6月6日 · Interleukin-1 receptors and inhibitors of IL-1 signaling. a IL-1R1 interacts with both IL-1α and IL-1β and promotes signal transduction, together with its co-receptor IL-1R3 (IL …

IL1B is a gene that encodes the proinflammatory cytokine IL-1β, which plays a crucial role in the central nervous system by inducing various behavioral changes and responses to stress. You …

2010年1月19日 · Once activated, it orchestrates the inflammatory response by secreting proinflammatory cytokines, such as interleukin-1 (IL-1)–type cytokines, in particular IL-1β. IL-1 …