HCT 116 is an adherent cell line isolated from the colon of a patient with colon cancer. It has a mutation in codon 13 of the ras-proto-oncogene. This cell line is near-diploid and has a …

Understanding the roots and basic traits of HCT116 cells, such as their morphological features, genetic makeup, and cellular dimensions, is essential for researchers embarking on studies …

The HCT116 VIM RFP reporter cell line carries a knock-in red fluorescent protein (RFP) reporter, which was integrated before the stop codon at the last exon of the endogenous vimentin (VIM) …

We tested this hypothesis by exposing cancerous HCT116 or non-cancerous NCM460 colon cells to physiologically relevant doses of butyrate. Cellular responses to butyrate were …

Here, we report the building of two QSAR studies using molecular and NMR descriptors for the prediction of anticancer activity against the human colon carcinoma HCT116 cell line, using …

2008年6月15日 · HCT116 human colon cancer cell line in this in vivo model system provides a tool to dissect the molecular mechanism involved in the metastatic cascade. This orthotopic …

HCT 116-Luc2 is a cell line exhibiting epithelial morphology that was isolated in 2018 from the colon of an adult male patient with carcinoma colorectal. This cell line can be used in assay …

2019年12月5日 · We investigated β-catenin localization, transcriptome, and phenotypic differences of HCT116 cells containing a wild-type (HCT116-WT) or mutant β-catenin allele …

The stable Id4 overexpressing HCT116 cells (HCT116-Id4) were screened with puromycin at 1.5 μg/ml (Sigma) for at least one week. The Id4 expression was confirmed by quantitative PCR …

2017年7月27日 · In this study, we established MARCH2 knockout HCT116 cell lines using CRISPR/Cas9-mediated genome editing to evaluate the role of MARCH2 in colon cancer in …