G3BP1 Gene - GeneCards | G3BP1 Protein | G3BP1 Antibody
2025年3月30日 · G3BP1 (G3BP Stress Granule Assembly Factor 1) is a Protein Coding gene. Diseases associated with G3BP1 include Chikungunya and Glioma Susceptibility 1 . Among …
G3BP1 Is a Tunable Switch that Triggers Phase Separation to …
2020年4月16日 · The molecular basis for stress granule assembly is a network of protein-RNA interactions with G3BP1 as the central node and molecular switch that triggers phase …
G3BP1 promotes DNA binding and activation of cGAS - Nature
2018年12月3日 · G3BP1 enhanced DNA binding of cGAS by promoting the formation of large cGAS complexes. G3BP1 deficiency led to inefficient DNA binding by cGAS and inhibited …
G3BP1 G3BP stress granule assembly factor 1 [ (human)]
2025年2月9日 · G3BP1 promotes human breast cancer cell proliferation through coordinating with GSK-3beta and stabilizing beta-catenin. G3BP1 binds to guanine quadruplexes in mRNAs to …
G3BP1 Is a Tunable Switch that Triggers Phase Separation to ... - PubMed
2020年4月16日 · Here, we show that SGs assemble through liquid-liquid phase separation (LLPS) arising from interactions distributed unevenly across a core protein-RNA interaction network. …
The multi-functional RNA-binding protein G3BP1 and its potential ...
Ras-GTPase-activating protein (GAP)-binding protein 1 (G3BP1) is a multi-functional protein that is best known for its role in the assembly and dynamics of stress granules. Recent studies …
The roles of G3BP1 in human diseases (review)
2022年5月5日 · Ras-GTPase-activating protein binding protein 1 (G3BP1) is a multifunctional binding protein involved in a variety of biological functions, including cell proliferation, …
G3BP1 enhances cytoplasmic DNA pattern recognition - Nature
2018年12月11日 · The stress-granule protein G3BP1 forms a high-molecular-weight protein complex with the sensor cGAS and enhances its detection of cytoplasmic DNA.
G3BP1 controls the senescence-associated secretome and its
2020年10月5日 · Here, we show that the rasGAP SH3-binding protein 1 (G3BP1) is required for the activation of the senescent-associated secretory phenotype (SASP). During senescence, …
G3BP1 ribonucleoprotein complexes regulate focal adhesion …
Boraas et al. identify that mRNAs and the stress granule RNA-binding protein G3BP1 form ribonucleoprotein (RNP) complexes at FAs. These RNPs regulate FA protein mobility and cell …
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