According to recent studies and observations in clinical practice, uterine fibroids increase the risk of preterm birth. There are several theories on the pathogenesis of preterm birth in the presence of fibroids. One theory proclaims that fibroid necrosis leads to preterm birth, though pathophysiological mechanisms have not been described.

Case: A 28-year-old G1, P0 woman at 20 weeks gestation developed systemic inflammatory response syndrome with acute renal failure and massive ascites secondary to a ruptured degenerated fibroid. This resulted in preterm delivery and neonatal death. At 6 weeks postpartum, she successfully underwent an abdominal myomectomy.

Pregnant women with fibroids are significantly more likely to develop preterm labor and to deliver preterm than women without fibroids (16.1% vs 8.7% and 16% vs 10.8%, respectively; Table 1). 7 Multiple fibroids and fibroids contacting the placenta appear to be independent risk factors for preterm labor. 10, 19 In contrast, fibroids do not ...

2022年7月22日 · According to recent studies and observations in clinical practice, uterine fibroids increase the risk of preterm birth. There are several theories on the pathogenesis of preterm birth in the presence of fibroids. One theory proclaims that fibroid necrosis leads to preterm birth, though pathophysiolo …

2020年7月1日 · In the context of pregnancy, this presentation of a ruptured degenerated fibroid clearly carries a risk of preterm delivery. In pregnant patients, closely monitoring for preterm labour and cervical dilatation is imperative, especially given that the pain of the degenerating fibroid can mask potential uterine contractions.

This is a rare case of uterine fibroid rupture causing preterm labour and systemic inflammatory response syndrome. This report discusses the diagnosis of uterine rupture related to the fibroid with imaging and subsequent management, which included fertility-preserving surgery.

Although most pregnancies are unaffected by the presence of uterine fibroids, large submucosal and retro-placental fibroids seem to impart a greater risk for complications, including pain (degeneration), vaginal bleeding, placental abruption, IUGR, and preterm labor and birth.

degenerated fibroid clearly carries a risk of preterm deliv-ery. In pregnant patients, closely monitoring for preterm labour and cervical dilatation is imperative, especially given that the pain of the degenerating fibroid can mask potential uterine contractions. This …

Fibroids in pregnancy usually remain asymptomatic, but may present with pain from fibroid degeneration. Fibroids may increase risk of (1) Preterm labor. Abnormal fetal presentation. Placenta previa and placental abruption. Early pregnancy loss or miscarriage . Postpartum hemorrhage. Rarely, fibroids partially obstruct the vagina.

2024年12月6日 · Regarding fibroid degeneration, while our dataset did not include specific information on this variable, sensitivity analyses excluding preeclampsia with severe features reinforced the association between fibroids and preterm birth, supporting the need for additional research into degeneration as a potential mechanism.