2025年4月1日 · cuer (plural cuers) One who cues . 2010 , Carol J. LaSasso, Kelly Lamar Crain, Jacqueline Leybaert, Cued Speech and Cued Language Development for Deaf and Hard of Hearing Children :

The copper efflux regulator (CueR), a representative member of mercury resistance regulator (MerR) family metalloregulators, controls expression of copper homeostasis-regulating genes in bacteria. The mechanism of transcription activation by CueR ...

2020年9月28日 · Structural analysis of transcription activation complex comprising E. coli transcription factor CueR, RNAP holoenzyme and promoter DNA reveals that CueR distorts the DNA conformation to promote...

2021年5月21日 · CueR controls the transcription of two copper-homeostasis genes, copA encoding a Cu +-transporting P-type ATPase pump and cueO encoding a copper oxidase for detoxification (Outten et al., 2000; Petersen and Moller, 2000; Stoyanov et al., 2001; Yamamoto and Ishihama, 2005).

The copper efflux regulator (CueR) is a classical member of the MerR family of metalloregulators and is common in gram-negative bacteria. Through its C-terminal effector-binding domain, CueR senses cytoplasmic copper ions to regulate the transcription of genes contributing to copper homeostasis, an …

2025年4月1日 · Callers and Cuers: If you reside in Utah and are not listed here, please Add Caller or Cuer.

Strep_CueR A78C is able to activate copA expression in a copper-responsive manner (Figure 3C), while substitution of one of the two copper-binding cysteines (Strep_CueR C112S) inactivated CueR (Figure 3D).

Copper efflux regulator (CueR) is a Cu+- and Ag+-sensing metalloregulator that controls the expression of two genes involved in metal homeostasis: CopA, which encodes a copper/silver ATPase, and CueO, which encodes a copper oxidase [2].

2003年9月5日 · An unusual buried metal-receptor site in CueR restricts the metal to a linear, two-coordinate geometry and uses helix-dipole and hydrogen-bonding interactions to enhance metal binding. This binding mode is rare among metalloproteins but …

Moreover, copper-responsive regulation of yacK depends upon the presence of cueR. The cueR deletion strain shows a loss of copper activation at the yacK promoter (Fig.2 B). By providing the cueR gene intrans on a low copy number plasmid (Fig. 3 B), copper induction of yacK is restored.