
肉碱棕榈酰转移酶 1B(CPT1B)基因 | MCE - MCE-生物活性 ...
由该基因编码的蛋白质是肉碱/胆碱乙酰转移酶家族的成员,是肌肉线粒体中长链脂肪酸 β-氧化途径的速率控制酶。 这种酶是长链脂肪酰辅酶 A 从细胞质净运输到线粒体所必需的。 已发现该基 …
Nature重磅!抑制脂肪酸氧化能让心脏再生? - 知乎专栏
为了确定FAO在体内调节CM增殖和生长的作用,研究团队构建了αMHC-Cre pos/+;Cpt1b fl/fl小鼠(以下简称Cpt1b cKO),其中Cpt1b基因在胚胎阶段的CM中特异性失活。
CPT1B Gene - GeneCards | CPT1B Protein | CPT1B Antibody
2025年3月30日 · CPT1B (Carnitine Palmitoyltransferase 1B) is a Protein Coding gene. Diseases associated with CPT1B include Carnitine Palmitoyltransferase I Deficiency and Chanarin …
Inhibition of fatty acid oxidation enables heart regeneration in …
2023年9月27日 · Inhibition of the fatty acid oxidation metabolic pathway through inactivation of Cpt1b enhances cardiomyocyte survival and proliferation and allows heart regeneration in …
CPT1B基因的功能与作用机制解析 - 八方基因
2024年12月30日 · CPT1B,全称为肉碱棕榈酰转移酶1B(carnitine palmitoyltransferase 1B),是一种位于22号染色体q13.33区域的基因。 这个基因编码的蛋白质也被称为 M-CPT1 或 CPT1 …
CPT1B carnitine palmitoyltransferase 1B [ (human)]
CPT1B, a metabolic molecule, is also an independent risk factor in CN-AML. Low carnitine palmitoyltransferase 1 activity is a risk factor for narcolepsy type 1 and other hypersomnia. …
CPT1B carnitine palmitoyltransferase 1B [ Homo sapiens (human) ]
2025年2月8日 · Title: Targeting CPT1B as a potential therapeutic strategy in castration-resistant and enzalutamide-resistant prostate cancer. Low expression of CPT1B in high-grade urinary …
The muscle isoform, CPT1b, is the predominant isoform expressed in the heart. It has been suggested that inhibiting CPT1 activity by specific CPT1 inhibitors exerts protective effects
Nature:抑制脂肪酸氧化可使成年小鼠心脏再生 - 知乎
为了确定FAO在体内调节CM增殖和生长的作用,研究人员构建了Cpt1b敲除(Cpt1b cKO)小鼠,其中Cpt1b基因在胚胎阶段的CM中特异性失活。 观察发现,与对照小鼠相比, Cpt1b cKO …
Cpt1b carnitine palmitoyltransferase 1b, muscle [ (house mouse)]
2025年2月8日 · Cardiac CPT-1b suppression protects against the aggravation of cardiac morphology and function associated with HFD feeding. CPT-1b represents a potential …