Cdc25 activates cyclin dependent kinases by removing phosphate from residues in the Cdk active site. In turn, the phosphorylation by M-Cdk (a complex of Cdk1 and cyclin B) activates Cdc25. …

2020年12月1日 · 艾美捷科技作为专业的生命科学领域解决方案供应商，为您推荐的细胞分裂周期因子25 (Cdc25)检测试剂盒，可用于高通量蛋白磷酸酶Cdc25A、Cdc25B和Cdc25C的抑制剂 …

Cell division cycle 25 (CDC25) phosphatases are key regulators of the eukaryotic cell cycle. They are required to control cyclin-dependent kinase (CDK) dephosphorylation and activation in a...

The Cdc25 phosphatases are cell cycle control proteins whose overexpression is frequently associated with a wide variety of cancers. In this review of the Cdc25 phosphatases, we first …

2020年6月3日 · CDC25C is a cyclin of the specific phosphatase family that activates the cyclin B1/CDK1 complex in cells for entering mitosis and regulates G2/M progression and plays an …

CCDC25存在于癌细胞的表面，可以高特异性和亲和性与NET DNA结合，使癌细胞能够感知NET。 令人印象深刻的是，研究者们还鉴定出了CCDC25与NET DNA结合的特定细胞外部分。 研究 …

Members of the eukaryotic Cdc25 phosphatase family are key targets of the Chk1 and Chk2 checkpoint kinases, which inactivate Cdc25 to halt cell cycle progression when DNA is …

2015年1月30日 · Cdc25C (cell division cycle 25C) phosphatase triggers entry into mitosis in the cell cycle by dephosphorylating cyclin B-Cdk1. Cdc25C exhibits basal phosphatase activity …

Cell division cycle 25 A (Cdc25A), a dual-specificity protein phosphatase, is one of the most crucial cell cycle regulators, which removes the inhibitory phosphorylation in cyclin-dependent …

Cell Division Cycle-25 (CDC25) plays an important role in transitions between cell-cycle phases by dephosphorylating and activating CDKs. CDC25B and CDC25C play a major role in G2/M …