CD36 is a membrane glycoprotein present on platelets, mononuclear phagocytes, adipocytes, hepatocytes, myocytes, and some epithelia. On microvascular endothelial cells, CD36 is a receptor for thrombospondin-1 and related proteins and functions as a ...

2025年3月28日 · CD36 (CD36 Molecule (CD36 Blood Group)) is a Protein Coding gene. Diseases associated with CD36 include Platelet Glycoprotein Iv Deficiency and Coronary Heart Disease 7. Among its related pathways are Toll Like Receptor 7/8 (TLR7/8) Cascade and Epigenetic regulation by WDR5-containing histone modifying complexes.

CD36 is a type 2 cell surface scavenger receptor widely expressed in many immune and non-immune cells. It functions as both a signaling receptor responding to DAMPs and PAMPs, as well as a long chain free fatty acid transporter.

CD36 is a scavenger receptor that functions in high affinity tissue uptake of long chain fatty acids (FA) and contributes under excessive fat supply to lipid accumulation and metabolic dysfunction. This review describes recent evidence regarding the ...

2020年9月21日 · Restricting CD36 at either palmitoylated or depalmitoylated state eliminates its FA uptake activity, indicating an essential role of dynamic palmitoylation of CD36.

CD36 is a class B scavenger receptor that binds various ligands such as AGE, oxLDL, fatty acids, collagen, thrombospondin, and anionic phospholipids. It is highly expressed in macrophages and macrophage-derived foam cells in atherosclerotic plaques.

2001年9月15日 · CD36, identified more than a quarter of a century ago as a platelet integral membrane glycoprotein (glycoprotein IV), was until recently best known as a receptor for thrombospondin-1 (TSP-1).

2014年6月6日 · CD36, a protein found on the surface of various immune cells and blood vessel cells, is a key component of atherosclerosis.

CD36, a membrane glycoprotein presenting on the surface of cells, binds fatty acids to facilitate their transport for lipid utilization. Upregulated CD36 expression has been observed in multiple cancer types including acute myeloid leukemia, breast cancer, colorectal cancer, gastric cancer, etc.

CD36 is a membrane glycoprotein present on platelets, mononuclear phagocytes, adipocytes, hepatocytes, myocytes, and some epithelia. On microvascular endothelial cells, CD36 is a receptor for throm...