
BCL6 - Wikipedia
The protein encoded by the BCL6 gene is a zinc finger transcription factor that has three evolutionarily conserved domains. BCL6 contains a (1) N-terminal BTB/POZ domain (Broad …
BCL6 Gene - GeneCards | BCL6 Protein | BCL6 Antibody
2025年3月30日 · BCL6 (BCL6 Transcription Repressor) is a Protein Coding gene. Diseases associated with BCL6 include Intravascular Large B-Cell Lymphoma and High-Grade B-Cell …
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BCL6功能及其调节剂在肿瘤中的研究进展
多项研究表明通过靶向抑制或降解BCL6 可有效遏制肿瘤生长,有望为这些肿瘤提供新的治疗手段。 本文就BCL6功能、调节剂类别及其在肿瘤中的研究进展进行综述。 Abstract: B-cell …
医学院祁海课题组揭示BCL6调控滤泡辅助T细胞的细胞免疫学新机 …
8月30日,清华大学医学院祁海课题组在《免疫》(Immunity) 期刊 上在线发表了题为“BCL6控制滤泡T-B细胞间接触依赖性辅助信号传递”(BCL6 controls contact-dependent help delivery …
B-cell Lymphoma 6 (BCL6): From Master Regulator of Humoral …
2022年12月2日 · In this review, we summarize what is known of BCL6 (role, effect, mechanisms) in pediatric cancers, highlighting the two sides of BCL6 function, humoral immunity, and …
B-cell Lymphoma 6 (BCL6): From Master Regulator of Humoral
2022年12月2日 · B-cell lymphoma 6 (BCL6) is a protooncogene in adult and pediatric cancers, first identified in diffuse large B-cell lymphoma (DLBCL) where it acts as a repressor of the …
打破癌细胞的“不死金身”!《自然》:斯坦福团队设计全新分子, …
而 B细胞淋巴瘤蛋白6(BCL6) 就是促进癌细胞增殖的重要推手。 作为一种转录抑制因子,BCL6会抑制参与细胞凋亡的基因表达。 它们在DLBCL中常常会功能失调,大量结合细胞凋 …
B Cell Lymphoma 6 (BCL6): A Conserved Regulator of Immunity …
2024年10月11日 · BCL6 is critical for germinal center (GC) formation and the development of high-affinity antibodies, with key roles in the generation and function of GC B cells, follicular …
BCL6: master regulator of the germinal center reaction and key …
BCL6 is a transcriptional repressor which has emerged as a critical regulator of germinal centers (GC), the sites where B cells are selected based on the production of antibodies with high …
B 细胞淋巴瘤 6 (BCL6):从体液免疫的主调节因子 ... - X-MOL
在这篇综述中,我们总结了 bcl6 在儿科癌症中的已知信息(作用、效果、机制),重点介绍了 bcl6 功能、体液免疫和肿瘤发生的两个方面,并回顾了 bcl6 抑制剂并强调了有待改进的领域小 …