Angiotensin-converting enzyme 2 (ACE2) [5] is an enzyme that can be found either attached to the membrane of cells (mACE2) in the intestines, kidney, testis, gallbladder, and heart or in a soluble form (sACE2).

Angiotensin-converting enzyme (ACE) and its homologue, ACE2, are commonly allied with hypertension, renin–angiotensin–aldosterone system pathway, and other cardiovascular system disorders.

2020年5月14日 · The ACE2 receptor allows the virus that causes COVID-19 to infect and destroy our cells. What is the normal role of ACE2 in the body, and could it be the key to blocking infection?

Angiotensin-converting enzyme 2 (ACE2), discovered as a homologue of ACE, acts as its physiological counterbalance providing homeostatic regulation of circulating angiotensin II (Ang II) levels. ACE2 is a zinc metalloenzyme and carboxypeptidase ...

2020年5月16日 · ACE2 acts as the receptor for the SARS-CoV-2 virus and allows it to infect the cell. ACE2 is a protein on the surface of many cell types. It is an enzyme that generates small proteins – by cutting up the larger protein angiotensinogen – that …

Angiotensin-converting enzyme 2 (ACE2) is not only an enzyme but also a functional receptor on cell surfaces through which SARS-CoV-2 enters the host cells and is highly expressed in the heart, kidneys, and lungs and shed into the plasma. ACE2 is a key regulator of the renin–angiotensin–aldosterone system (RAAS).

2025年3月27日 · ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility.

2020年6月5日 · The angiotensin converting enzyme-2 (ACE-2) has been identified as the receptor for the SARS-CoV-2 viral entry. As such, it is now receiving renewed attention as a potential target for anti-viral therapeutics.

2020年3月26日 · Role of angiotensin converting enzyme 2 (ACE2) in the renin-angiotensin system (RAS) and proposed mechanism for severe acute respiratory syndrome coronavirus-2 (SARS–CoV-2)–induced downregulation of cell surface ACE2 expression.

2025年3月30日 · ACE2 (Angiotensin Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Covid-19 and Coronavirus Infectious Disease. Among its related pathways are ACE Inhibitor Pathway, Pharmacodynamics and Early SARS-CoV-2 …