乙醛脱氢酶 - 百度百科
负责人体内乙醛转化的主要是肝中的乙醛脱氢酶（aldh），它有两种 同功酶 ，分别分布于胞质溶胶（aldh1）与线粒体（aldh2）。 两者在催化速率上有很明显的差异，ALDH2对乙醛的 K_M 低 …
Cancer Research:揭示肿瘤干细胞标志物ALDH1A1通过重塑免疫微 …
2021年12月26日 · 近日，复旦大学生物医学研究院/附属肿瘤医院柳素玲团队在Cancer Research杂志在线发表了题为ALDH1A1 activity in tumor-initiating cells remodels myeloid-derived …
Frontiers | ALDH1: A potential therapeutic target for cancer stem …
2022年10月27日 · ALDH1 is positively correlated with helicobacter pylori infection. When ALDH1 is overexpressed, it mainly restores the reduction of drug resistance caused by miR-625 …
ALDH1A1 Gene - GeneCards | AL1A1 Protein | AL1A1 Antibody
2025年3月30日 · ALDH1A1 (Aldehyde Dehydrogenase 1 Family Member A1) is a Protein Coding gene. Diseases associated with ALDH1A1 include Alcohol Dependence and Anaerobic …
The Significance of Aldehyde Dehydrogenase 1 in Cancers - PMC
ALDH1A proteins play a key role in many biological processes, such as development, homeostasis, and tumorigenesis, through their enzymatic activity in retinoic acid (RA) signaling …
ALDH1 is a marker of normal and malignant human mammary stem cells …
In a series of 577 breast carcinomas, expression of ALDH1 detected by immunostaining correlated with poor prognosis. These findings offer an important new tool for the study of …
The Significance of Aldehyde Dehydrogenase 1 in Cancers - MDPI
2024年12月30日 · The goal of this paper is to discuss the role of ALDH isozymes in different cancers, review advances in ALDH1-targeting cancer therapies, and explore a mechanism …
Aldehyde Dehydrogenase 1 (ALDH1) Is a Potential Marker for
2015年4月27日 · Recent studies have demonstrated that aldehyde dehydrogenase 1 (ALDH1) is a marker for CSCs in adult cancers. Although CSCs have been identified in some different …
Aldehyde dehydrogenase 1A1 in stem cells and cancer
2016年3月8日 · The human genome contains 19 putatively functional aldehyde dehydrogenase (ALDH) genes, which encode enzymes critical for detoxification of endogenous and …
The role of human aldehyde dehydrogenase in normal and …
In addition, emerging evidence suggests that ALDH1 is not only a marker for stem cells, but may also play important functional roles related to self-protection, differentiation, and expansion. …