AKT1 - Wikipedia
The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth …
AKT 丝氨酸/苏氨酸激酶 1（AKT1）基因 | MCE
蛋白磷酸酶通过使 Akt 或 PIP3 去磷酸化而充当 Akt 蛋白的负调节剂。 PI3K/Akt 信号通路对肿瘤细胞存活至关重要。存活因子可以通过激活 Akt1 以转录非依赖性方式抑制细胞凋亡，然后磷酸 …
AKT1 靶点介绍及实验小贴士 | abcam 中文官网
AKT1（丝氨酸和苏氨酸激酶 AKT）也被称为蛋白激酶 B (PKB)。 AKT1 由胰岛素和多种生长和存活因子激活，在调节细胞生长和分裂和细胞凋亡抑制等多种过程中发挥着关键作用。 AKT 家 …
AKT1 Gene - GeneCards | AKT1 Protein | AKT1 Antibody
2025年3月30日 · AKT1 (AKT Serine/Threonine Kinase 1) is a Protein Coding gene. Diseases associated with AKT1 include Proteus Syndrome and Cowden Syndrome 6. Among its related …
Defining the Akt1 interactome and its role in regulating the cell …
Akt1, a serine/threonine kinase, is a multi-functional protein implicated in regulation of cell growth, survival and proliferation. Though it has a role in G1/S progression, the manner by which Akt1 …
实力靶点AKT：名门将子 破茧待蝶 - 知乎 - 知乎专栏
目前，akt丝氨酸/苏氨酸激酶家族共发现了三种高度同源的亚型，即akt1（pkbα）、akt2（pkbβ）和 akt3（pkbγ）。 AKT三种亚型分别由39个氨基酸铰链区隔开的N端pleckstrin …
AtKC1 inhibits AKT1 activation via its amino-terminal inhibitory …
2025年2月19日 · In the AKT1–AtKC1 complex, interactions between the I-domain of AtKC1 and the C-linker of an adjacent AKT1 subunit induce a rotation of the C-linker toward the I-domain, …
AKT1重组蛋白：关键信号分子的功能与临床应用 - 知乎
akt1蛋白，也称为蛋白激酶b（pkb），是细胞信号传导途径中的一个关键分子，参与调控细胞生长、存活、代谢和分化等多种过程。 重组AKT1蛋白的研究为理解其在多种疾病中的角色提供了 …
AKT1 AKT serine/threonine kinase 1 [ Homo sapiens (human) ]
2025年3月9日 · CRLF1 bridges AKT and mTORC2 through SIN1 to inhibit pyroptosis and enhance chemo-resistance in ovarian cancer.
AKT1 gene - MedlinePlus
The AKT1 gene provides instructions for making a protein called AKT1 kinase. This protein is found in various cell types throughout the body, where it plays a critical role in many signaling …