2025年2月25日 · Acid chlorides react with ammonia to give amides, by an addition-elimination path, and these are reduced to amines by LiAlH 4 (Section 21-7). Alkyl halides can be …

The method allows the conversion of aliphatic acids, including pivalic acid, aromatic acids, and primary and secondary amines and tolerates acids bearing unprotected alcohol, phenol, and …

2025年2月25日 · identify the product formed when a given amine reacts with a given acid chloride. identify the amine, the acid chloride, or both, needed to synthesize a given amide. …

The direct conversion of a carboxylic acid to an amide is difficult because amines are basic and tend to convert carboxylic acids to their highly unreactive carboxylates. In this reaction the …

An achiral amine in combination with a catalytic amount of a chiral Brønsted acid can accomplish an aldol addition-dehydration-conjugate reduction-reductive amination with 2,6-diketones to …

The Schmidt Reaction can be employed to either get amides by reacting the azide with a ketone or to get an amine by reacting the azide with a carboxylic acid. The chemical reaction wherein …

A compound 'A' on reduction with iron scrap and hydrochloric acid gives compound 'B' with molecular formula C 6 H 7 N. Compound 'B' on reaction with CHCl 3 and alcoholic KOH …

Both Hofmann and Curtius rearrangements convert a carboxylic acid derivative—either an amide (Hofmann) or an acid chloride (Curtius)—into a primary amine with loss of one carbon, RCOY …

In an identical reaction, EDC facilitates formation of amides from carboxylic acids: In both cases, the reaction works at room temperature with quite good yields (70-90 %). Aside from this, …

Primary and secondary (but not tertiary) amines can also be acylated by nucleophilic acyl substitution reaction with an acid chloride or an acid anhydride to yield an amide (Section 21.4 …