2017年2月23日 · NTDs are abnormalities that can occur in the brain, spinal cord, or spine of a developing fetus. Very early in the development of a fetus, certain cells form a tube (called the neural tube) that will later become the spinal cord, the brain, and the nearby structures that protect them, including the backbone (also called the spinal column or vertebrae).

2018年8月8日 · These tests might include an X-ray, magnetic resonance imaging (MRI), a computed tomography (CT or CAT) scan to look for spinal defects or excess fluid2; measuring the head circumference; assessing the infant’s strength, motor, and sensory functioning; and observing the infant’s urinary stream. 3

2018年8月17日 · Neural tube defects (NTDs) are problems that occur when the spinal cord, brain, and related structures do not form properly. Neural Tube Defects (NTDs) | NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development

2018年8月6日 · The exact causes of NTDs are not known. Many different factors, including genetics, nutrition, and environmental factors, are known to play a role.Research shows that getting enough folic acid (also known as folate or vitamin B9) before conception and early in pregnancy can greatly reduce the risk of spina bifida and other NTDs.

2016年5月20日 · In addition, taking 400 micrograms of folic acid daily reduces the risk for neural tube defects by 70%. 2,9 Most prenatal vitamins contain the recommended 400 micrograms of folic acid as well as other vitamins that pregnant women and their developing fetus need. 1,10 Folic acid has been added to foods like cereals, breads, pasta, and other ...

NICHD is one of several NIH institutes and other federal entities that support and conduct research on NTDs. NTDs, including spina bifida, are developmental malformations resulting from atypical or incomplete closure of the neural tube. NICHD conducts and supports research on the precursors of neural tube defects and their causes, detection, treatment, and effect on …

2012年4月12日 · Preventing neural tube defects. Research from NICHD and other organizations led the U.S. Public Health Service to recommend that all women capable of becoming pregnant get at least 400 micrograms of folic acid daily. Taking folic acid prior to conception can reduce the risk for neural tube defects, a primary goal of NICHD research.

2009年3月2日 · Because low folate levels are a known risk factor for neural tube defects, the researchers used statistical techniques to evaluate the role of Vitamin B12 independently of the role of folate. In all three groups, women with low B12 concentrations (estimated at less than 250 ng/L, before pregnancy) had 2.5-3 times the risk of having a child with ...

2018年3月23日 · Infants born with NTDs may have other conditions that need treatment. Such conditions vary from one infant to another, and some conditions develop or must be addressed over time or later in life. The most severe issues tend to develop in infants who have myelomeningocele, the most severe form of spina bifida.1 Associated conditions can include …

2023年12月19日 · Neural tube defects, such as spina bifida, and problems related to the growth and development of the brain and spinal cord Functional or Developmental Congenital Anomalies Functional or developmental congenital anomalies are related to a problem with how a body part or body system works or functions.