How COVID-19 Causes Loss of Smell - Harvard Medical School
2020年7月24日 · Temporary loss of smell, or anosmia, is the main neurological symptom and one of the earliest and most commonly reported indicators of COVID-19. Studies suggest it better predicts the disease than other well-known symptoms such as fever and cough, but the underlying mechanisms for loss of smell in patients with COVID-19 have been unclear.
Anosmia in COVID-19: Mechanisms and Significance - PMC
We aim to review the pathophysiology of anosmia related to viral upper respiratory infections and the prognostic implications. Current evidence suggests that SARS-CoV-2-related anosmia may be a new viral syndrome specific to COVID-19 and can be mediated by intranasal inoculation of SARS-CoV-2 into the olfactory neural circuitry.
Anosmia in COVID-19: Underlying Mechanisms and Assessment …
We review recent progress in defining underlying cellular and molecular mechanisms of the virus-induced anosmia, with a focus on the emerging crucial role of sustentacular cells in the olfactory epithelium.
Management of Anosmia in COVID-19: A Comprehensive Review
Researchers have discovered that the neurological side effects of SARS-CoV-2 infection include acute anosmia and ageusia. This work aims to review the relevant mechanisms, provide information on COVID-19-related anosmia, and suggest a novel approach to treating long-term anosmia brought on by coronavirus disease.
Mechanisms of SARS-CoV-2-associated anosmia
2023年8月16日 · We propose that indirect mechanisms contribute to altered olfactory system function in COVID-19-associated anosmia, as opposed to neuronal infection or neuroinvasion into the brain.
Anosmia in COVID-19: Mechanisms and Significance - PubMed
We aim to review the pathophysiology of anosmia related to viral upper respiratory infections and the prognostic implications. Current evidence suggests that SARS-CoV-2-related anosmia may be a new viral syndrome specific to COVID-19 and can be mediated by intranasal inoculation of SARS-CoV-2 into the olfactory neural circuitry.
Mechanism of Anosmia Caused by Symptoms of COVID-19 and …
The occurrence of anosmia, the loss or change in sense of smell, is one of the most common symptoms of COVID-19 experienced by almost 53% of those affected. Several hypotheses explain the mechanism of anosmia in patients suffering from COVID-19.
Pathogenesis and progression of anosmia and dysgeusia during the COVID …
2022年10月9日 · The pathophysiology of COVID-19-associated dysgeusia is also currently unclear, though many hypotheses exist. In general, the most common etiologies of dysgeusia include head trauma, infections of the upper respiratory tract, exposure to toxic substances, iatrogenic causes, medicines and glossodynia [ 18 ].
Anosmia in COVID-19: A Bumpy Road to Establishing a
2024年8月5日 · Initial hospital observations and early studies have suggested several possible mechanisms for the development of anosmia in COVID-19, including olfactory cleft syndrome, nasal obstruction and rhinorrhea, cytokine storm, direct damage to olfactory receptor neurons (ORNs), and impairment of the olfactory perception centers in the brain.
Receptors Involved in COVID-19-Related Anosmia: An Update on …
2024年8月5日 · It will help to understand the underlying pathophysiology of virus-induced anosmia, which may help in finding and designing effective therapies targeting molecules involved in viral invasion and olfaction.