Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

The prescribed dosage for fluconazole may depend on your individual treatment plan. Other factors, including the specific diagnosis, age, and body weight, may affect your dosage of fluconazole.

When my co-founder and I started Invoice Home, we wanted to build a business that could grow over time. We noted many inefficiencies while discussing our past experiences working within ...

Table 1 below provides an overview of the key features of a prokaryotic cell: Table 1. The structure and function of key prokaryotic cell structures. Prokaryotes have ribosomes but they are smaller ...

A slightly lower siponimod clearance was observed in patients with MS than in healthy volunteers. The dosage regimen, body mass index, CYP2C9 genetic polymorphism and fluconazole combination may had ...

Three ways were proposed to explain the resistance mechanism: (1) the corresponding amino acids docked with azoles are changed, (2) the structure of the binding cavity is rearranged, leading to ...