This study presents important findings on cold tolerance shared between hibernating and non-hibernating mammals, identifying a key molecule, GPX4, through multi-species genome-wide CRISPR screens. The ...
Background: Ferroptosis is a novel type of programmed cell death characterized by excessive lipid peroxides and iron overload inside the cell. SLC7A11/GSH is one of the most important anti-ferroptotic ...
A recent study from the University of Würzburg unveiled a key enzyme involved in producing selenoproteins, opening new strategies for treating certain types of cancer in children.
Shanghai Tenth People’s Hospital, Shanghai Frontiers Science Center of Nanocatalytic Medicine, School of Medicine, Tongji University, Shanghai 200331, P. R. China Shanghai Tenth People’s Hospital, ...
A molecular pathway was established where the BR signal ... Cancer stem cells (CSCs) are an important factor in immune therapy resistance. Ferroptosis, a form of cell death driven by iron ...
Ferroptosis represents a distinct cell death pathway regulated by iron metabolism, ROS production, and lipid peroxidation. The primary trigger for ferroptosis involves excessive accumulation of ...