We further elucidated that ApoA1 activated NRF2, the transcription factor of SLC7A11, by promoting its nuclear translocation. Conclusion: Our results imply that HDL/ApoA1 inhibits macrophage ...

Mustafa Kaya - Radical-induced NRF2 signaling in Epithelial-Mesenchymal Transition and macrophage polarization Research Health and medicine ...

NRF2 is associated with tumor recurrence ... changes in immune cell composition, particularly T cells and macrophages, the major contributors to adipose inflammation and metabolic dysregulation.

Department of Medical Life Sciences, Department of Medical Sciences (Graduate School), and Catholic Photomedicine Research Institute, College of Medicine, The Catholic University of Korea, 222 ...

Deciphering the function of Xiangsha-Liujunzi-Tang in enhancing duodenal mucosal barrier by inhibiting MC/Tryptase/PAR-2 signaling pathway in functional dyspepsia rats.

Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.

This study shows that the key rate-limiting enzyme CPT1A in fatty acid oxidation, together with L-carnitine from tumor-associated macrophages ... loop enhances the NRF2/GPX4 system and reduces ...

Results The GCPM ecosystem coordinates a unique immunosuppressive pattern distinct from that of primary GC, which is dominated by a stroma-myeloid niche composed of SPP1+tumour-associated macrophages ...