However, the intricate mechanisms governing these processes have remained elusive due to the presence of multiple functional domains within Munc13, each playing distinct roles in neurotransmitter ...

Here, the authors show that EGF signalling may regulate cytoneme dynamics by maintaining basal plasma membrane levels of the Hedgehog co-receptor Ihog in the wing disc epithelium. Phagocytosed ...

Novo Nordisk’s bid to provide a once-weekly basal insulin product for people with diabetes, reducing the number of injections needed, has hit a major hurdle in the US. The FDA sent the Danish ...

Learn about idiopathic pulmonary fibrosis, its symptoms, diagnosis, and treatment options for managing this lung disease.

This study presents a valuable theoretical exploration on the electrophysiological mechanisms of ionic currents via gap junctions in hippocampal CA1 pyramidal-cell models, and their potential ...

Although it had long been thought that Ras signaling emanated only from the plasma membrane, Chiu et al. demonstrated in 2002 that palmitoylated H-Ras is resident on both plasma membrane and Golgi ...

Jan. 27, 2025 — Basal cell carcinomas, the most common form of skin cancer, occur in chronically sun-exposed areas such as the face. Locally advanced tumors in particular can be difficult to ...