Self-Perceived Barriers to Pediatric Cancer Care in Sub-Saharan Africa: A Cross-Sectional Multinational Study Asparaginase (ASN) is a critical component of pediatric ALL protocols. Until recently, ASN ...

Scientists showed combining the classic drug asparaginase (chemotherapy) with a newer drug, venetoclax (a BCL-2 targeted therapy), was most effective at treating B-ALL in laboratory models.

SMILE: Dexamethasone, methotrexate, ifosfamide, L-asparaginase and etoposide. Stage I/II Involved-field radiotherapy of at least 50 Gy, followed by chemotherapy with non-MDR-dependent drugs ...