A new study led by Profs. Fan Kelong and Yan Xiyun from the Institute of Biophysics of the Chinese Academy of Sciences ...

银屑病是一种慢性、非传染性的皮肤病，表现为红色斑块覆盖银色鳞屑，常伴有瘙痒或疼痛等显著不适。银屑病患者的皮肤病变区域表现出异常升高的活性氧（ROS）水平，这些高水平的ROS会引发氧化应激和DNA损伤，进而加剧皮肤炎症、角质形成细胞异常增殖和分化。然而 ...

A protein treated with a small-molecule inhibitor may still act as a scaffold for protein-protein interactions that would be disrupted by siRNA treatment. In other words, if an enzyme's physical ...

A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or ...

For the treatment of multidrug-resistant lung cancer, the system includes siRNA targeted to MRP1 and BCL2 mRNA, whereas breast and ovarian cancers require siRNA targeted to MDR1 and BCL2 mRNA.

Registration Link for Presentation and live Q&A to take place, Wednesday March 5, 2025 at 12:00 pm EST Marlborough, ...

The company’s second development candidate, ATL-101, is a di-siRNA designed to silence the HTT gene for the treatment of Huntington’s disease. Huntington’s disease is a progressive ...

Furthermore, co-treatment of tirzepatide, a GLP-1/GIP receptor co-agonist, with ALK7 siRNA enhanced the therapeutic benefits versus tirzepatide monotherapy, with additive effects on body weight ...

PASADENA, CA, USA I February 25, 2025 I Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced preclinical results on ARO-ALK7, the company’s ...