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8 天
转录因子TCF4作为内在无序枢纽蛋白的分子特性研究:揭示神经发育 ...
在神经发育和认知功能调控的复杂网络中,基本螺旋-环-螺旋(basic helix-loop-helix, bHLH)转录因子家族扮演着核心角色。其中转录因子4(TCF4)的突变与Pitt-Hopkins综合征(PTHS)、精神分裂症等严重神经系统疾病密切相关,但学界对其分子特性的认知长期局限于bHLH ...
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