Physiological extracellular matrix (ECM) calcification or mineralization is restricted to bones, teeth and the hypertrophic zone of growth plate cartilage. In contrast, pathological ECM ...

The extracellular matrix protein fibronectin forms fibrils when in association with cells that exert tension. Cells apply enough force to stretch fibrils in vivo. Stretching of individual ...

Our group has explored the regeneration of soft biological tissues through cell-extracellular matrix interactions, with a focus on collagen-rich environments and fibrosis. We have developed a new ...

In addition to HSPG binding, HB-GAM has similar carbohydrate binding sites in chondroitin sulfate proteoglycans (CSPGs). CSPGs are major inhibitory regulators of plasticity and regeneration in the CNS ...

Tech millionaire Bryan Johnson, known for his anti-aging endeavors, experienced a setback during his "Project Baby Face" ...

A study at MedUni Vienna's Department of Dermatology provides insights into the diversity of cancer-associated fibroblasts in ...

A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment. The results ...