Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

The authors reported no benefit of low-dose dopamine over saline in this high-risk patient population undergoing coronary angiography. In fact, a subset of patients with peripheral vascular ...

These results suggest that the cardiovascular responses caused by lateral habenula activation are mediated by the dopaminergic system, specifically by dopamine neurons in the ventral tegmental area.

intermittent oral doses of levodopa induce discontinuous stimulation of striatal dopamine receptors. This pulsatile stimulation leads to molecular and physiologic changes in basal ganglia neurons ...

At Reviva we are focused on developing a drug that targets both the serotonin and dopamine receptor signaling ... No cardiometabolic, cardiovascular, prolactin or endocrine complications were ...

These results suggest that the cardiovascular responses caused by lateral habenula activation are mediated by the dopaminergic system, specifically by dopamine neurons in the ventral tegmental area.

Scientists had previously identified the functions of two distinct pathways and types of dopamine receptors in the forebrain: the D1 receptors, which activate neurons, and the D2 receptors ...

Another common cause of atypical parkinsonism is “vascular parkinsonism” caused by multiple and usually very small ... In contrast to typical PD, in which dopamine receptors are spared, patients with ...

Bromocriptine activates post-synaptic dopamine receptors. The dopaminergic neurons ... Psychosis. Dementia. Cardiovascular disease (eg, MI, arrhythmias). Galactose intolerance, severe lactase ...

The mechanism of the drug's beneficial effect on cardiovascular disease remains to be determined. Recently, timed-release bromocriptine (Cycloset), a sympatholytic dopamine D 2 receptor agonist ...

The study also used radioactive iodine labeling and single photon emission computed tomography to visualize dopamine receptors in the brain. Consistent with previous studies, individuals with ...