But while constraint models have been highly effective for identifying disease-causing variants in the nuclear genome, they have not been useful for mutations in the mitochondrial genome ...
Small cellular organelles called mitochondria contain ... The clinical symptoms of this disease are associated with the administration of a particular type of antibiotic (Prezant et al., ...
Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA). This condition can cause symptoms including muscle weakness, ...