After dry powder inhalation to COPD patients at steady state, urinary excretion was 7% (1.3mcg) of the unchanged dose over 24 hours. The renal clearance of tiotropium exceeds the creatinine ...

Two to four inhalations of the metered dose inhaler can be used prn for acute symptoms or pre-exercise to block exercise induced bronchospasm. Use an assist device such as the Maxair Autohaler (3M ...