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揭秘细胞迁移 “密码”:细胞外渗透压通过 TRPV4 - Rho/ROCK 信号通路 ...
结果表明,细胞外渗透压显著影响成骨细胞迁移,低渗促进、高渗抑制,且通过 TRPV4 - Rho/ROCK 信号通路调控。这为理解骨重塑机制提供新视角。 在骨骼的 “微观世界” 里,成骨细胞(osteoblasts)如同勤劳的 “工匠”,对维持骨骼的健康与完整起着关键作用。
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