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生物通
10 天
不同成纤维细胞亚型通过 TNFR1 信号传导驱动小鼠回肠炎的空间特异性 ...
在炎症性肠病(IBD)中,克罗恩病(CD)主要影响回肠末端。为探究其发病机制,研究人员利用 Tnf ΔARE 小鼠模型开展回肠炎相关研究。结果发现不同成纤维细胞亚型在回肠炎的起始和进展中起关键作用,这为 CD 的治疗提供了新方向。 克罗恩病(Crohn’s disease,CD ...
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