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Microglial TLR4-Lyn 激酶:阿尔茨海默病治疗的新希望
为探究 TLR4-Lyn 通路在阿尔茨海默病(AD)中的作用,研究人员以 WT、5XFAD 和 5XFAD x Lyn-/-小鼠为模型开展研究。结果发现 Lyn 激酶可调节 TLR4 诱导的炎症和 Syk 诱导的保护,TLIMs 能改善 AD 症状,为 AD 治疗提供新策略。 在神经科学领域,阿尔茨海默病(Alzheimer’s ...
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