Cognigenics’ initial therapeutics are designed to selectively downregulate the 5-hydroxytryptamine receptor 2A (5HT2A) post-synaptic neuronal receptors—a serotonin receptor subtype—in the ...

The theoretical basis for and clinical experience with using oral serotonin type 3 (5-HT 3)-receptor antagonists for preventing chemotherapy-induced emesis are discussed. Evidence supports the ...

A surrogate test that may have clinical relevance is the duration of inhibition at 5-HT 3 receptors located on cutaneous afferent neurons. Intradermal injection of serotonin produces a flare ...

Psychedelics are a class of drugs that induce different states of consciousness , with classic psychedelics such as mescaline, psilocybin, DMT a ...