The interplay between aging and cellular senescence reveals insights into chronic inflammation and potential strategies for enhancing healthspan and longevity.

近日，国家生物信息中心（中国科学院北京基因组研究所）张维绮研究团队与中国科学院动物研究所刘光慧团队合作，在Science China Life Sciences在线发表题为“RIG-I-driven CDKN1A stabilization ...

衰老诱导剂顺铂处理促进 βTrCP1 过表达细胞死亡 ：顺铂是一种广泛用于治疗实体肿瘤的化疗药物，但它可能导致肿瘤细胞进入衰老状态。研究人员用不同浓度的顺铂处理细胞，确定了能诱导细胞衰老的最佳浓度。实验结果显示，在顺铂诱导衰老的情况下，βTrCP1 过表达的细胞数量明显减少，出现了细胞死亡的现象。在三维细胞培养中，过表达 βTrCP1 ...

For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which ...

Cellular aging involves growth arrest and epigenetic alterations, offering insights into therapeutic approaches for enhancing ...

Cell aging has always been an important topic in biological research, and telomere shortening is one of the key issues in ...

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery ...

Identification of CCNB1 as a biomarker for cellular senescence in hepatocellular carcinoma: a bioinformatics and experimental validation study 为探寻肝细胞癌（HCC）可靠诊断标志物和治疗靶点，安徽医科大学研究人员经生物信息分析和实验，发现 CCNB1 或为 ...