In contrast, 141 Fragment molecules exactly match Drug molecules, resulting in 107 unique Murcko scaffolds representing 20% of the Fragment-Drug scaffold overlap. Thus, the Bioactive-Drug scaffold ...

Bifloranes, also known as serrulatanes, feature a distinct 6,6-bicyclic framework and a prenyl side chain, showcasing a wide ...

“They are unique. I haven’t seen any scaffold that is as strong and bioactive,” says Zreiqat. Bone is the most transplanted substance in medicine, with loss or damage resulting from ...

The research potentially heralds a future where joint replacement surgeries become significantly less common as patients ...

Instead of using dancing molecules, the new study ... The study, "A bioactive supramolecular and covalent polymer scaffold for cartilage repair in a sheep model," was supported by the Mike and ...