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NAD+/SIRT3轴通过调控海马突触可塑性介导母体分离诱导的认知障碍 ...
编辑推荐:早期应激如何导致精神分裂症相关认知缺陷?武汉大学团队发现NAD + /SIRT3轴通过调节线粒体功能和海马突触可塑性发挥关键作用。补充NAD + 前体(NAM)或激活SIRT3可逆转母体分离(MS)大鼠的线粒体形态异常、树突棘密度降低及长时程增强(LTP ...
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