为探究 MEF2C 调节小胶质细胞激活机制，研究人员开展相关研究，发现该通路及 CDK2 抑制剂作用，意义重大。 小胶质细胞内在免疫检查点是维持免疫稳态的重要保障，能防止小胶质细胞过度激活，这一过程对自闭症谱系障碍（ASD）等神经系统疾病影响显著。

Figure 1: Recruitment of cyclin E/Cdk2/Xic1 and SCF to replication origins. The third role of cyclin E/Cdk2 in Xic1 degradation is the recruitment of SCF components to chromatin 1, which is likely ...