The ROCKET AF trial compared rivaroxaban with dose-adjusted warfarin in patients with nonvalvular AF and a prior history of stroke or at least two other additional risk factors for stroke.
Janssen and Bayer have stopped a phase 3 trial of Xarelto early after results showed it can cut deaths, heart attacks and strokes compared to aspirin. The promising data paves the way for a ...
Bayer has launched a trial of its anticoagulant Xarelto in long-term, secondary prevention of blood clots. The EINSTEIN CHOICE study will investigate Xarelto (rivaroxaban) 10 mg and 20 mg once ...
Further trials comparing aspirin with newer anticoagulants (dabigatran, apixaban and rivaroxaban) are necessary to assess the role of each agent in stroke prevention in patients with AF.
The research team focused the study on the two most prescribed direct oral anticoagulants, or DOACs, rivaroxaban (brand ... to be confirmed with randomized trials. "In the absence of randomized ...