The molecule was found in soil samples collected from a laboratory technician’s garden. The discovery shows that “there is ...
A natural antibacterial molecule shows clinical promise. Its unusual binding site is on an excellent target: ...
7 天
News-Medical.Net on MSNNew peptide antibiotic stops bacteria by binding where no drug has beforeResearchers discovered lariocidin, a lasso peptide antibiotic that kills multidrug-resistant bacteria by binding a novel ...
Amid a surge in drug-resistant bacteria, researchers believe they have discovered a new class of antibiotics, three decades ...
However, the infection did modify the underlying molecular structure of the ribosome, leading to increased poxvirus protein translation. Genetic knockout screens coupled with metabolic assays ...
The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations ...
A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes. Dan is a News Editor at The Scientist. He writes and ...
1 First, the researchers generated stopless-ORF circular RNAs (socRNAs) that promoted continuous translation for extended periods of time. The researchers visualized translation, including ribosome ...
ReAberrant translation initiation at non-AUG start codons is associated with cancer and neurodegenerative diseases. Therefore, identifying how non-AUG translation is regulated differently from ...
14 天
News-Medical.Net on MSNA versatile toolbox sets gold standard for characterizing IRES activity in cellsOnly recently has the ribosome - one of the oldest molecular machines in evolutionary terms - been recognized as an active regulator of gene expression at the level of protein biosynthesis.
Bacteria can easily evolve, and can quickly gain resistance to drugs. Drug-resistant bacterial infections already cause the deaths of millions ... | Cell And Molecular Biology ...
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