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9 天
NAT10通过调控丝氨酸合成通路驱动乳腺癌脑转移的机制研究
脑转移是癌症患者死亡的主要原因之一,但治疗手段有限。为解决这一难题,研究人员通过体内外筛选发现N-乙酰转移酶10(NAT10)是脑转移的关键调控因子。研究表明,NAT10通过其RNA解旋酶结构域调控3-磷酸甘油酸脱氢酶(PHGDH)和磷酸丝氨酸氨基转移酶1(PSAT1 ...
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