However, the structure of the winged-helix protein, hRFX1, bound to DNA reported in a recent issue of Nature 1 has revealed a striking counter example to this rule. Figure 1: Structure of two ...

This Analysis covers the ribbon–helix–helix (RHH) transcription-factor superfamily of proteins and focuses ... DNA binding does not alter the structure of RHH-transcription factors, and ...

Scientists still needed to figure out this molecule's structure to be sure, and to understand how it worked. In 1948, Linus Pauling discovered that many proteins take the shape of an alpha helix ...