Solution NMR data on peptides can be acquired at concentrations > 0.1mM for a 1D or to get structural information >1-2mM in aqueous buffers with 10% D 2 O. Phosphate buffer is an economical ...

Structure determination by NMR typically requires a protein concentration of 0.5 mM or greater, stable for several days at the desired temperature, usually 20-40 o C. Proteins and peptides should be ...

The research in Professor Zagorski's group focuses on unraveling the molecular mechanisms associated with protein misfolding and amyloid formation. Numerous analytical techniques are utilized, ...

and is particularly beneficial for multi-dimensional experiments in biomolecular NMR, where time savings up to a factor of 4 in 3D experiments or 10 and even more in 4D and 5D experiments can be ...

receptor and µ-opioid peptide (MOP) receptor (dual-NMR) agonism. This dual-NMR agonist has the potential to deliver significant pain relief comparable to opioids with minimized risk of ...