Severe intraventricular hemorrhage—the primary outcome of the study—occurred at similar rates in the ibuprofen and placebo groups. Patent ductus arteriosus was significantly less frequent in ...

This article presents common misconceptions about the physiologic significance of early ductal shunting and reviews the evidence regarding the preferential use of echocardiography rather than ...

A patent ductus arteriosus (PDA) is a persistent connection between the aorta and the pulmonary artery resulting in left to right shunting. This connection is supposed to close shortly after birth ...

Once a PDA is suspected or confirmed, the 2 main questions are (1) how to treat and (2) when to treat a particular infant This clinical controversy recently was the subject of an excellent ...