Many PPI products are available ... PPIs bind to a certain type of protein called an enzyme that is located within the parietal cells, which line your stomach. This enzyme is the hydrogen ...

CYP2C19-mediated interactions Ticlopidine ↑ PPI effect Inhibition of omeprazole ... rapid metabolizers (with an increased enzyme activity), intermediate metabolizers (with moderate enzyme ...

Our lead investigational therapy, INZ-701, is an ENPP1 Fc fusion protein enzyme replacement therapy (ERT) designed to restore PPi and adenosine levels. INZ-701 is currently in late-stage clinical ...

We are experts in the PPi-Adenosine Pathway, where the ENPP1 enzyme generates inorganic pyrophosphate (PPi), which regulates mineralization, and adenosine, which controls intimal proliferation ...