Higher and more frequent PPI dosing than standard would be expected to raise the basal cure rate and thus the overall success rate, even if success related to the additional components remained ...

and PPI dose (high vs low). Overall association of PPI and CAP was analyzed using the random effects model (Comprehensive Meta analysis® Version 2.0). Nine studies met all criteria for the ...

The Association of Physicians of India (API) has recently issued a consensus statement, highlighting vonoprazan as an ...

Patients with GERD are usually treated with once-daily PPIs; however, studies have shown that 25–42% of patients treated with a standard-dose PPI continue to experience symptoms of GERD ...

Use the lowest dose of Protonix and for the shortest duration of PPI therapy appropriate to the condition. PPI therapy may be associated with a greater risk of osteoporosis-related fractures of ...

The Phase I study demonstrated for the first time that high doses of orally administered PPI-1011 were well-tolerated, even with repeated dosing up to 14 days. All adverse events that were possibly or ...