CD8+ T细胞在免疫防御中扮演关键角色,特别是在抗病毒和抗肿瘤免疫反应中。调节CD8+ T细胞的活化与效应功能是提高免疫治疗效果的关键。蛋白磷酸 ...
编辑推荐:针对丝氨酸/苏氨酸磷酸酶缺乏特异性抑制剂的难题,Lindsey A. Allan团队开发了"directSLiMs"系统,通过药物诱导的SLiM肽 ...
A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...