PKB/AKT, protein kinase B; S6K, ribosomal protein S6 kinase.) However, the discovery of the way in which 'primed' substrates dock with GSK3 might have opened up a new opportunity to develop ...

The results painted a rather different picture to that described above: IL-4, a good activator of PKB/Akt but not of mitogen-activated protein (MAP) kinase, failed to induce endogenous BAD ...

Autophagy is regulated by key cell signaling pathways such as Akt (protein kinase B, PKB), mammalian target of rapamycin (mTOR) and AMP-activated protein kinase (AMPK) involved in cell survival and ...

Department of Radiation Oncology, Radboud University Nijmegen Medical Centre, Netherlands Activation of the phosphatidylinositol-3-kinase (PI3-K)/protein kinase B (AKT) pathway is associated with ...

(b) Densitometric evaluation of the relevant protein bands. Data are the means of at least three independent ... (2013) Inhibition of mTORC1 by SU6656, the selective Src kinase inhibitor is not ...