One target for such inhibition, the p38 mitogen-activated protein kinase (MAPK) signaling cascade, has a role in inflammation by mediating the cellular response to stress, pathogens, and cytokines.
爱思益普可提供MAP2K4靶点筛选服务。MAP2K4采用ADP-Glo方法进行筛选。ADP-Glo是一种通过量化激酶反应期间产生的 ADP 的量来测量激酶活性的方法,也是一种通用、均相、高通量筛选的方法。该测定分两步进行:首先,在激酶反应后,加入 ...
Alzheimer’s disease remains one of the most pressing challenges in modern medicine, ranking as a leading cause of death ...
Previous laboratory and clinical studies showed that inhibiting the activation of the MAPK signaling pathway could attenuate acute lung injury.