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Nature
7 个月
The as-yet unfulfilled promise of p38 MAPK inhibitors
One target for such inhibition, the p38 mitogen-activated protein kinase (MAPK) signaling cascade, has a role in inflammation by mediating the cellular response to stress, pathogens, and cytokines.
10 天
MAP2K4靶点介绍|靶点筛选服务|靶点检测服务
爱思益普可提供MAP2K4靶点筛选服务。MAP2K4采用ADP-Glo方法进行筛选。ADP-Glo是一种通过量化激酶反应期间产生的 ADP 的量来测量激酶活性的方法,也是一种通用、均相、高通量筛选的方法。该测定分两步进行:首先,在激酶反应后,加入 ...
The Brighterside of News on MSN
2 天
AI-powered ‘Alzheimer’s in a Dish’ model revolutionizes new drug development
Alzheimer’s disease remains one of the most pressing challenges in modern medicine, ranking as a leading cause of death ...
BioWorld
3 天
GSK-3179106 reduces inflammation and acute lung injury in mice through p38 MAPK targeting
Previous laboratory and clinical studies showed that inhibiting the activation of the MAPK signaling pathway could attenuate acute lung injury.
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