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鼻腔初免 - 皮下加强的三价 OMV 疫苗:牙周炎防治新希望
细菌外膜囊泡(OMV)作为一种新型疫苗平台,具有独特优势。OMV 是纳米级的蛋白脂质体,不仅携带病原体特异性抗原,还包含病原体相关分子模式,如脂多糖(LPS)、脂蛋白、肽聚糖和 DNA/RNA 等,能够通过与宿主免疫系统相互作用引发免疫反应。例如,鞭毛缺陷 ...
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