By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.
该研究揭示了肠道神经系统(ENS)通过机械力敏感蛋白 Piezo1 直接感知肠道内机械力,从而调控胃肠蠕动和 免疫 稳态。这一发现不仅揭示了消化系统机械感知的分子机制,还为炎症性肠病(IBD)及胃肠动力障碍等疾病提供了全新的治疗靶点。
胃肠道 (GI) 在协调消化和屏障免疫的过程中会经历多种机械力。这些过程的核心调控者是肠神经系统 ...
Powerful chemical biological techniques have now been developed to decipher the dynamic stability of the synapses and to further interrogate the complex properties of neuronal circuits.
A team of researchers has identified a mechanism that regulates the production of two different proteins from the same gene.
How does the brain retain a sequence of events in memory? Researchers from the University Hospital Bonn (UKB), the University ...
Neurodegenerative conditions such as Parkinson's disease and Alzheimer's involve progressive neuronal loss due to ...
为了解决这一问题,第四军医大学等机构的研究人员开展了相关研究。研究成果发表在《Experimental & Molecular Medicine》杂志上。该研究对于明确七氟醚对人类神经元发育的影响,以及为临床麻醉的安全使用提供指导具有重要意义。
A team of researchers from the Institute for Neurosciences, a joint center of the Spanish National Research Council (CSIC) ...
Brain functions stem from and rely on electrical signals created and propagated by neurons. As such, scientists measure electrical signals to study neuronal function at both single-cell and systemic ...
Mitochondria play a crucial role in maintaining energy balance and cellular health. Recent studies have shown that chronic ...